Emirates will operate a one-off A380 service to Manila next Monday.
The Gulf carrier currently flies three-times daily to the Philippines capital. It first flew the Dubai to Manila route in 1990.
On October 7, an Emirates superjumbo will depart Dubai International Airport as EK334 at 0920 and arrive in Manila at 2210. Return flight EK8335 will leave Manila at 0115 the next day and land in in Dubai at 0540.
The flight is to mark the airline's move to the International Terminal (T3) at Ninoy Aquino International Airport.
Barry Brown, Emirates' divisional senior vice president, commercial operations east, said: "In 2013, Emirates welcomed over 820,000 passengers on its three daily Dubai to Manila services with a very high average seat factor.
"Bringing our flagship A380 to Manila is a fantastic way to celebrate our move to the new international terminal and also our commitment to the Philippines."
Emirates currently operates 53 A380s to 31 destinations. Click here to read our guide to the airline's superjumbo fleet.