Easyjet is launching a London Gatwick to Tel Aviv service on April 1.
The budget airline will operate the three-times weekly route on Tuesdays, Thursdays and Sundays.
It will be Easyjet's third route between the UK and Tel Aviv - it already flies to the Israeli city from Manchester and Luton.
Hugh Aitken, the airline's UK commercial manager, said: "We expect to carry around 50,000 passengers each year on the new Gatwick service.
"Combined with our flights from London Luton and Manchester this means we will operate 16 weekly flights to Tel Aviv from the UK."
The carrier is also increasing its flights between Manchester and Tel Aviv from two to three per week between February 17 and April 28.
Earlier this week, Easyjet launched a Chinese website (see news, December 3), while last month it announced two new routes from Gatwick to Brussels and Strasbourg for March (see news, November 19).
Graham Smith