Air France has this week launched a thrice-weekly service between Paris Charles De Gaulle and Panama City.
The national carrier is deploying a Boeing 777-200 on the route, which began on Monday.
The aircraft is in a three-class configuration with 309 seats — 35 in business, 24 in premium economy and 250 in economy.
Flights to and from Panama City will operate on Mondays, Thursdays and Saturdays, with the outward-bound AF474 service departing Paris at 1330 and arriving in Panama City at 1830 local time.
Return flight AF475 leaves Panama City at 2200 and lands at Charles De Gaulle at 1410 the following day.
This winter, Air France-KLM will serve 25 destinations in Central and South America and the Caribbean, with over 200 weekly flights departing from Paris-Charles de Gaulle and Amsterdam-Schiphol.
Frederic Gagey, chairman and CEO of Air France, said: "Air France is continuing to expand in areas of high economic development. With the launch of a new route to Panama City, we have confirmed our position as leader in Central and South America and the Caribbean.
"We are strengthening our presence in the region and are offering our customers numerous connecting opportunities via the Copa Airlines hub at Panama City-Tocumen airport."