I can see the direct aisle being a preference for many. I for one, try to select 10B on B777s with the drawback of the galley/lavatory nearby and 64A on the upper deck when I travel BA.
When I fly the more conventional 2-2-2 offers like LH and SK, I aim for an aisle seat in the middle section to avoid the climb over.
The 2-2-1, 1-2-2 staggered approach that Swiss, Finnair, Austrian and Brussels offer (to name a few) leaves 4 of 5 seats with direct aisle access. When travelling alone, I aim for a single seat. If I am with a companion, I go for the two seats in the middle.
Despite the lack of aisle access, I find the BA CW seat preferable to many of the above alternatives for one simple reason; the openness around me. The Contour seats, as they slide down into the seat in front, have a coffin like experience. I sense more of the “sardine-like” feeling from this, then the eight seats across on BA.