In case of any doubt talk to your doctor who prescribed it or the pharmacist. Especially if you use other medication as well or have to use them for quite a long time.
If they can’t help you, you can contact the medical travel centers that most major airlines/airports have. They are normally quite knowledgeable and professional about it.
Don’t experiment with Malarone or any prescription drug for that matter. It can have some nasty side effects or interactions.